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For patients who have not previously been diagnosed with vitamin B12 deficiency or prescribed a vitamin B12 injection, the medicine can be offered if vitamin B12 deficiency is suspected based on signs, symptoms and/or risk factors, though confirmation of vitamin B12 deficiency by a reliable test kit should also be considered

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Meanwhile, CO actively promoted the production of the anti-inflammatory cytokine class IL-10 [59]

Interactions Between Genetic, Lifestyle and Environmental Risk Factors for Multiple Sclerosis