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To account for multiple comparisons, we used a Bonferroni correction (corrected p -value: 0.05/15 = 0.003)

Under normal conditions, the activity of the Nrf2-mediated transcription is low, as most of Nrf2 protein is degraded in the proteasome ( REGULATORY MECHANISMS OF NRF2 ACTIVITY Keap1 was identified as a cytoplasmic Nrf2-interacting protein that negatively regulates Nrf2 activity (Wakabayashi et al., 2003)

Sulforaphane is produced upon plant damage and activates production of extracellular reactive oxygen species (ROS) to neutralize external threats, such as pathogens (Rahman et al., 2022

So: the ingredient category is real, the mechanism is plausible, and the evidence at studied doses is positive but heterogeneous

Int J Pharm Pharm Sci 3:1822 Cocoman A, Murray J (2008) Intramuscular injections: a review of best practice for mental health nurses