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Recommendation: NuMedica suggests taking four capsules after a meal once per day or as directed by your healthcare practitioner

Your doctor can review your hormone profile and monitor safely if fertility is a concern

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Their potential mechanism of action would be the inhibition of prostaglandins and cytokines, including endothelin 1 and granulocyte macrophage colony-stimulating factor (GM-CSF), which are the main stimulators of melanin production (Menter, 2004)

One explanation for this may be that as long as the intake of protein is sufficient, serum IGF-I levels will remain relatively stable (115), i.e., the intake of calories per se does not alter serum IGF-I levels