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Nutrition, blood sugar balance, inflammation, and lifestyle all play important roles in long-term cognitive function
In terms of molecular function, the most enriched categories included alcohol dehydrogenase activity ( ADH7 , ADH4 , AAD4 ), chaperone binding and protein folding ( SSA4 , HSP82 , FES1 , CPR6 ), oxidoreductase activity ( GRE2 , OYE3 , SRX1 , FRE7 ), zinc ion transmembrane transporter activity ( ZRT1 ), carbonic anhydrase activity ( NCE103 ), and putative ubiquitin ligase activity ( ASI3 )
6k) due to reduced NAD + regeneration which resulted in a lower NAD + /NADH ratio (Fig