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Causes of Glutathione Depletion: Aging Chronic stress Poor diet (low in sulfur-rich foods) Toxin exposure (pollution, alcohol, drugs) Certain diseases (diabetes, HIV, liver disease) How to Boost Glutathione Levels: Diet: Sulfur-rich foods (garlic, onions, cruciferous vegetables) High-quality protein (whey protein, eggs, lean meats) Foods rich in selenium (Brazil nuts, fish) and vitamin C (citrus fruits, berries) Supplements: Liposomal glutathione (better absorption) N-acetylcysteine (NAC) A precursor to glutathione Alpha-lipoic acid (ALA) Recycles glutathione Lifestyle: Regular exercise (moderate intensity) Adequate sleep Reducing toxin exposure Medical & Cosmetic Uses: Used in IV therapy for detox, immune support, and chronic illnesses
Regulation of lipid biosynthesis and glycolipid metabolism by butyrate can also occur in the liver by being converted into FAs, cholesterol and ketone bodies (166)
eGFR was calculated using the following CKD-EPI formula: eGFR = 186 serum creatinine 1.154 age 0.203 (0.742 if female)
Fatty acid elongase 6 is an endoplasmic reticulum enzyme that inhibits GPX4 and GSH expression and ferritin heavy chain 1 (FTH1) activity by interacting with ACSL4, leading to ROS accumulation [142, 143]
Ketamine can block muscarinic acetylcholine receptors, resulting in anticholinergic symptoms such as hypertension, tachycardia, and bronchodilation
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