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Br J Ind Med

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This review systematically elucidates the multifaceted effects of DM-induced metabolic disturbances on the lung, with a focus on four key pathophysiological axes triggered by hyperglycemic homeostasis, including chronic inflammation, oxidative stress imbalance, endocrine network disruption, and intestinal dysbiosis

In another study, significantly higher ratios of oxidized to reduced glutathione and significantly lower activities of glutathione peroxidase were detected in whole blood and peripheral mononuclear cells in hypertensive patients compared to normotensive volunteers re, a finding supported by another study reporting significantly lower GSH and higher GSSG values in mononuclear cells from hypertensive subjects compared to controls (19)

Alcohol 2(3):437441 Jung YS, Kim SJ, Kwon DY, Ahn CW, Kim YS, Choi DW, Kim YC (2013) Alleviation of alcoholic liver injury by betaine involves an enhancement of antioxidant defense via regulation of sulfur amino acid metabolism