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L-arginine is a conditionally essential amino acid, meaning that under normal circumstances, the body can synthesize sufficient L-arginine, but certain health situations can increase the demand for L-arginine beyond the bodys ability to make it

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Sudhir K, Elser MD, Jennings GL, Komesaroff PA

Many studies to date have had a small sample size, meaning that very few people took part in the research

However, the true picture of high-dose vitamin Cs impact on immunity is more nuanced and complex than often