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In 20 minutes after stopping: Blood pressure and heart rate fall In 12 hours: Levels of carbon monoxide become normal In 2 weeks to 3 months: Improvements in blood circulation and increased lung efficiency In 1 to 9 months: Improvement in coughing and breathing In 5 years : 50% reduction in risk of oral cancer than those who keep smoking After 10 to 15 years: Risk level similar to non-users Practical Steps to Quit Smoking: Establish a quitting date: Select a definite date within two weeks' time Inform family members and friends: Get their encouragement and support Get rid of triggers: Dispose of all tobacco-related items, including lighters and ashtrays Detect craving patterns: Maintain a diary that records your reasons for smoking Replace tobacco with other activities: Chewing gum, carrying a stress ball, or engaging in some other activity Get professional assistance: Using nicotine-replacement therapy (patches, gum, lozenges), bupropion, and varenicline doubles your chances of success Join a support group: Face-to-face or virtual Also read: How Do You Stop Bleeding Gums
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Feeling very angry or nervous when the effects of the drug begin to fade
In vitro experiments have shown that tobacco smoke extract activates the MAPK/AP-1 signaling pathway and promotes aberrant proliferation of urothelial cells 23 , while nicotine contributes to tumor progression and chemoresistance through activation of the PI3K/AKT/mTOR signaling axis 24
