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Research utilizing single-cell Raman microspectroscopy has demonstrated that ME/CFS patients exhibit significant aberrations in ROS clearance pathways, including elevated oxidative stress markers and reduced antioxidant enzyme activity
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This suggests that glutathionylation of one of these cysteine residues may be an intermediate toward the formation of the intermolecular disulfide in isoforms possessing both cysteines
Free Radical Biology and Medicine
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