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3.3 Solar elastosis or dermal extracellular matrix abnormality Chronic exposure to UV radiation can induce unusual accumulation of elastic tissue which can lead to the photoaging process, called solar elastosis

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identify an unexpected metabolic underlying mechanism for this disease: the lipid chaperone fatty-acid-binding protein 5 (FABP5) aggravates psoriatic inflammation by driving keratinocytes into ferroptosis, a form of regulated cell death induced by iron-dependent lipid peroxidation (Fig