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Recovery & System Regulation Research: Exploring how DSIP may be involved in system-wide recovery signaling, regulatory coordination, and neurobiological equilibrium

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If initial daily administration has been maintained for more than 2 weeks, extending this washout to 57 days allows fuller recovery from any receptor downregulation that may have occurred

If pain, range of motion, or function has not moved by week 4, the dose or delivery method needs adjusting rather than extending the same protocol blindly