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postulated the role of indoxyl sulfate in the pathogenesis of renal anemia: indoxyl sulfate could stimulate oxidative stress and induce eryptosis through Organic Anion Transporter 2 (OAT2)- and NADPH oxidase-dependent, as well as GSH-independent mechanisms [257]

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doi: 10.1074/jbc.M708523200 262 SonM.PuttaparthiK.KawamataH.RajendranB.BoyerP

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It does this especially by protecting you from damaging UVA and UVB rays from the sun