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In other embodiments, when an even more viscous medium is desired, the biocompatible gel comprises at least about 35%, at least about 45%, at least about 55%, at least about 65%, at least about 70%, at least about 75%, or even at least about 80% or so by weight of the active agent

doi: 10.1016/j.freeradbiomed.2020.09.013

Strong dual CYP3A4/P-gp inhibitors (ketoconazole, ritonavir, clarithromycin) can double apixaban exposure [1]

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administered 100 mg/day for 4 weeks to athletes, and significant improvements were observed in biomarkers of muscle damage, antioxidant status, glutathione homeostasis, and without adverse effects [80]