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Numerous enzyme families catalyze reactions in this phase, including non-CYP metabolizing enzymes, such as aldehyde oxidases/dehydrogenase (AO/ALDH), NAD(P)H quinone reductase (NQR), hydrolases (epoxide hydrolase (EH), esterases/amidases), and conjugating enzymes, such as glutathione-s-transferases (GSTs), UDP-glucuronosyl transferases (UGTs), sulfotransferases (SULTs), and N-acetyl transferases (NATs)
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