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Astrocytes become dysfunctional after TBI, and, specifically within the hyperacute period, they can significantly contribute towards secondary injury by propagating excitatory cytotoxicity, cellular edema, neuroinflammation, and dysregulated metabolism [72]

The well-known geriatrician-haematologist Larry Solomon, working at Yale University in the USA, wrote 20 years ago: if I had treated only those people who actually had too low serum B12 and elevated MMA values, then I would not have treated approximately two-thirds of the people with a favourable response to B12 supplementation (note: partly via injections, partly via oral supplementation)

The GABAergic deficit hypothesis of major depressive disorder

Hydroxocobalamin is a natural, bioavailable form of Vitamin B12, essential for DNA synthesis, red blood cell formation, and neurological function

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