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Testicular cancer, testicular trauma, testicular torsion (rotation of the testis, which can cut off blood flow), surgeries that affect testicular blood flow, and abnormal testicular development are some other testicular causes of infertility

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Mechanisms underlying neuroprotection include enhanced cerebral angiogenesis supporting tissue oxygenation, anti-inflammatory effects reducing secondary injury, antioxidant activity limiting free radical damage, and modulation of neurotransmitter systems including the dopamine/glutamate/NO system