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Description

Its primary function is G-actin sequestration TB4 binds monomeric actin with nanomolar affinity, regulates the polymerizable actin pool, and indirectly governs cytoskeletal dynamics during cell migration, wound healing and inflammatory response

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Kamachi K , Akiyama H, Zhao R, Zhang L, Gupta SK, Ostermann LB, Otsuki Y, Nagano O, Saya H, Taguchi A, Andreeff M , Ishizawa J

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