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It has been shown that E3 ligase retinoblastoma binding protein 6 (RBBP6) promotes k48-linked ubiquitination of estrogen-related receptor (ERR), exacerbates mitochondrial damage in proximal renal tubular cells, promoting the development of diabetic kidney disease[9]

Quercetin, when co-administered along with doxorubicin, also suppressed tumour growth in vivo and was accompanied by minimal side effects [190]

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