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Disruption of this coordination, whether through mitochondrial dysfunction leading to decreased CPT1 activity or insufficient substrate supply for FAO, can cause energy imbalance in the myocardium

10.1186/s12920-024-01893-9 145 SheikholeslamiS.Zarif-YeganehM.FarashiS.AziziF.KiaS

Topical GHK-Cu is often recommended in the literature due to better evidence than injections

Frontiers in Molecular Biosciences 1: 9

These peripheral approaches, when combined with molecular, imaging, and behavioral measures, underscore the need to evaluate biomarkers not in isolation but as part of an integrative framework, setting the stage for broader implications in both research and clinical practice