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Additive neuroprotective effects of creatine and cyclooxygenase 2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis

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However, direct agonist stimulation of dopaminergic receptors present on NSCs in the SVZ, to promote adult neurogenesis, may represent the most clinically promising approach for PD patients when taking into consideration the substantial loss of dopaminergic neurons at the time of disease diagnosis [113, 127]

However, other studies have shown a negative impact on sperm motility and morphology with anti-retroviral treatments