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To understand why, it helps to look at what may break down inside the system when chronic stress pushes it past its limits

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Each of the features (i.e., focal thickening of the alveolar membranes, congestion, pulmonary edema, intra-alveolar hemorrhage, interstitial neutrophil infiltration, and intra-alveolar neutrophil infiltration) was scored (03) as absent (0) or present to a mild (1), moderate (2), or severe (3) degree, and a final histology score was determined

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a puffer is one type