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Alterations in catalase expression are responsible for various diseases, such as neurological disorders (Alzheimers disease, Parkinsons disease), psychiatric disorders (bipolar disorder, schizophrenia), cardiovascular diseases (hypertension), metabolic diseases (diabetes mellitus, autoimmune diseases (vitiligo)), Wilsons disease, and cancer (Fig

A hallmark of ferroptosis is iron-dependent lipid peroxidation, which could be inhibited by the key ferroptosis regulator Gpx4, free radical trapping antioxidants and ferroptosis-specific inhibitors 501

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Doege H, Baillie RA, Ortegon AM, Tsang B, Wu Q, Punreddy S, Hirsch D, Watson N, Gimeno RE, Stahl A (2006) Targeted deletion of FATP5 reveals multiple functions in liver metabolism: alterations in hepatic lipid homeostasis

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