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It acts as an antioxidant that delays cell damage and detoxifies chemicals in the liver

Dec 2008;30(6):543-545

Frequently Asked Questions FOXO4-DRI is used in laboratory studies investigating cellular senescence, apoptosis signaling, and FOXO4p53 interaction pathways

This unexpected sequence (named here I- Gpx4 ) was detected in control HT22 cells (treated with vehicle), but more interestingly, that its expression level was subjected to significant upregulation by DHA treatment (near 100% compared to control cells), which was in the range observed for the changes in expression for the set of other Gpx4 mRNA variants (Figure 2)