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Excess extracellular free iron enters neurons through the TF-TfR pathway, causing iron overload and inducing subsequent lipid peroxidation (Wan et al., 2019

doi:10.3389/fmicb.2024.1435720 40

The peptide acts as a signaling molecule, influencing gene expression i n approximately 31% of the hum an genome, promoting tissue regeneration, collagen synthesis , and antioxidant protection.