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Among other things, chemicals in cigarette smoke cause the cells that line blood vessels to become swollen and inflamed, which leads to narrowing of those vessels

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Cobb CO, Foulds J, Yen MS, Veldheer S, Lopez AA, Yingst JM, et al

The statement also calls for studies to include people with pre-existing cardiopulmonary disease, such as coronary artery disease or chronic obstructive pulmonary disease, to compare the effects of e-cigarette use with traditional smoking and how people who use both types of nicotine delivery may be affected