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Patients with pulmonary hypertension may be treated with epoprostenol, an intravenous prostaglandin, and bosentan, an oral endothelin-1 antagonist

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There is considerable literature about the oddities of the prescribing habits of British doctors , the factors influencing them, and the attitudes of doctors to prescription, but there have been as far as we know, no attempts to compare quantitatively the expected amount prescribed, on the basis of good clinical practice, with that actually prescribed