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The daily oral dose depends on age and weight: from 0 to 2 years, 150 mg per kg of body weight is recommended, from 2 to 6 years, 100 mg per kg, from 6 to 12 years, 75 mg per kg, over 12 years and in adults, 2 - 4 grams according to the severity of the pathology and the doctor's judgment

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(PubMed) Li J, Zhu Y, Zhou Y, et al

A reasonable hypothesis is that the rapid cycling allows the liver to respond quickly to the glutathione requirements of other tissues

Randomized comparison of oral and transdermal hormone replacement on carotid and uterine artery resistance to blood flow