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Because it didn't clearly work, it was not approved as a weight-loss drug, and development stalled

The principle remains consistent: mechanism dictates timing, and bioavailability depends on administration discipline

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Cell Host Microbe 26 (2), 265-272.e4

Global loss of desnutrin/ATGL gene function in mice resulted in increased weight gain and a shift in favor of carbohydrate over fat as a primary fuel source during fasting, indicating that in vivo desnutrin/ATGL likely also functions in adipose tissue lipolysis (43)