Questions remaining include optimal human dosing, long-term safety, effects across different populations, interactions with diet and exercise, and whether benefits extend beyond weight loss to improvements in cardiometabolic disease outcomes
(PubMed) Amagase H, Petesch BL, Matsuura H, Kasuga S, Itakura Y
Ethics statement The animal study was reviewed and approved by Kanazawa University Animal Experiment Committee
doi: 10.3389/fcell.2026.1813085 Received 18 February 2026 Revised 27 March 2026 Accepted 06 April 2026 Published 29 April 2026 Volume 14 - 2026 Edited by Maja Jazvinak Jembrek, Rudjer Boskovic Institute, Croatia Reviewed by Yi Wu, Chinese Academy of Sciences (CAS), China Brindha Devi P., Vels Institute of Science Technology and Advanced Studies, India Updates Copyright 2026 Ye, Hong, Liu, Wang, Zhang, Zheng, Yu and Wang
No other company in this space has such an odd price structure