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Chemicals NNMT inhibitors and standards for LC/MS/MS studies were purchased from established commercial suppliers or synthesized in-house by established synthetic schemes as described previously.[17] SAM, NA, 1-MQ, 1,8-diMQ, NAD + , and 6-chloro nicotinamide (6-CN) were obtained from Sigma-Aldrich (St

Similar content being viewed by others Introduction Exhibiting significant phenotypic heterogeneity, autism spectrum disorder (ASD) represents a developmental disorder defined by social interaction differences alongside restricted interests as well as stereotyped behaviors, with onset typically occurring in early childhood 1

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