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The PICOs elements were defined as follows: P (Participants): subjects of any age diagnosed with Vitamin B12 deficiency

Convenience: For individuals with busy lifestyles or difficulty remembering to take daily supplements, B12 injections offer a convenient solution

It's worth noting that recovery follows a predictable pattern: blood cell production typically begins improving within 3-5 days, haemoglobin rises over 1-2 months, while neurological recovery may take several months

Most reactions resolve spontaneously upon continued use or dose adjustment