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However, this dose-response relationship is not entirely linear, as even light smoking can substantially elevate risk, suggesting that using pack-years as an indicator may not fully capture smoking-related harm

If a contaminated bud reaches the consumer, the risk becomes a health issue

Some small sample or early trials have shown positive signals, but data from larger-scale, randomized controlled trials are still scarce, so its clinical feasibility and long-term risks need to be carefully evaluated (155, 156)

Unlike smoking and vaping, Zyn is smoke- and tobacco-free but the pouches still contain nicotine, an addictive chemical