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In the context of PMOS, the oxidative stress connection is directly relevant: studies confirm that granulosa cells from PMOS patients exhibit obvious inflammation and oxidative stress, with significantly reduced proliferation and increased apoptosis

Antioxidant vitamin supplement use and risk of dementia or Alzheimer's disease in older adults

Most injection site reactions resolve within hours

In addition, previous studies have found BBB disruption due to MMP-9 activation in patients and animal models (264), and the decrease levels of tight junction protein and adhesions protein in spinal cord (265)