glutathione transferases Glutathione-S-Transferases as Potential Targets for Modulation of Nitric Oxide-Mediated Vasodilation Glutathione S-transferases in kidney and

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CYP1-4 enzymes play an important role in the oxidative metabolism of fatty acids, steroids, polycyclic aromatic hydrocarbons (PAHs), various drugs such as acetaminophen, caffeine, clozapine, phenacetin, clomipramine and naproxen, and other carcinogens and environmental pollutants 73,74

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Notably, participants in the 12mg group had not reached a weight loss plateau at 48 weeks, suggesting that longer treatment durations could yield even greater reductions