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intense neuronal activity can deplete intracellular ATP, leading to K_ATP channel opening and a consequent reduction in firing, serving as a dynamic, activity-dependent brake on excessive excitation in the auditory brainstem (de Siqueira et al., 2025)

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Structural and functional characterization of the mutant Escherichia coli glutaredoxin (C14S) and its mixed disulfide with glutathione

This conversion requires the enzyme glutamatecysteine ligase (GCL, glutamate-cysteine synthase)

Prats-Puig et al