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When oxidized, it forms into a form known as a dimer (GSSG), and after interaction with a reducing agent such as vitamin C, can returned to the active state, without loss of function

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It just showed that SULT1E1 was likely involved and that combinations of SULT variants plus GST variants were likely deleterious.[ref] Another cell line genome-wide study found more than 22 genes related to susceptibility to acetaminophen-induced liver damage