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For example, animal studies show mast cells in the colon release prostaglandin E2, causing pain and hypersensitivity in IBS (irritable bowel syndrome)

El colgeno desempea un papel crucial en la cicatrizacin de heridas y la reparacin de tendones , ligamentos y msculos

While DSIP was primarily believed to be involved in sleep regulation due to its apparent ability to induce slow-wave sleep in rabbits, subsequent studies on the subject have been contradictory