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Kuang, F., Liu, J., Tang, D., & Kang, R

Secondly, HOCl/OH can activate enzyme complexes involved in DNA repair (such as APE1, PARP, DNA ligase) to assemble at DNA damage sites, promoting chromatin decondensation and further enhancing NETs/NETosis [247]

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For instance, an in vitro study using human neural stem cell line reported oxidative stress, DNA damage and apoptosis after 4 days of exposure to 30 nm polystyrene (PS) nanoparticles, observations which may correlate with potential pathway for cellular damage and neurodevelopmental disorders (Martin-Folgar et al., 2024)