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If we go beyond this enormous significance of Complex 1 of the mitochondrial respiratory chain for Parkinsons and just look at what the main theory about how it happens in the first place, its a degeneration of the dopamine-based neurons in the basal ganglia that are controlling movement

The abnormal presence of mitochondria in circulating red blood cells cause an increased oxygen consumption rate, ROS generation and hemolysis in patients with sickle cell disease

Identifying Alcohol-Related Liver Stress GGT is especially sensitive to alcohol intake, even at moderate levels

It directly activates fibroblasts, the cells responsible for producing collagen and other structural proteins

So weve been trying that approach as well in my lab for over a decade, and it does have great effects actually