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IV administration achieves near-100% bioavailability and shows 4045% reduction in hangover severity when given within 46 hours of drinking

Escalating the dose of a single compound eventually hits diminishing returns or triggers dose-dependent side effects without proportional metabolic benefit

3,32 In adults with DJS, the intensity and frequency of jaundice are stable over time

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Y.TaylorI.et al (2021)