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These microbial chemicals can act on the ENS and vagus or reach the brain to modulate neurotransmission, neuroinflammation, and neuronal health, representing a direct molecular link between gut bacteria and brain function

6 Evaluation of neurotransmitter concentrations 6.1 Dopamine assay In the presence of hydrochloric acid, dopamine oxidizes to form an indole derivative that binds to trihydroxyindoles and forms a fluorescent complex, whose absorbance at 485 nm is proportional to the concentration of dopamine (44)

Wei X, Ma K, Cheng Y et al (2020) Adhesive, conductive, self-healing, and antibacterial hydrogel based on chitosan-polyoxometalate complexes for wearable strain sensor

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To boost electro-catalytic activity and increase the rate of electron transfer, for instance, carbon NMs like graphene and carbon nanotubes (CNTs) have been added to CH-based ECSs (Shukla et al., 2018