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[DOI] [PMC free article] [PubMed] [Google Scholar] 22.Mercincavage M, Saddleson ML, Gup E, Halstead A, Mays D, Strasser AA

The harm-reduction approach taken in this Commentary recognizes that cigarettes kill and that if alternative nicotine systems are known with certainty to contain a small fraction of the toxins in cigarettes, this is sufficient to attempt to divert users away from the killer products toward the lower-risk ones, even with uncertainty surrounding the lifecycle health impacts of the latter