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E2F6, E2F7, and E2F8 are members of the E2F family of TF, which play important roles in cell cycle regulation, cell proliferation and survival, and gene expression 57

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Lucey, P

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This viral interference forces the cell to shift away from efficient aerobic respiration (oxidative phosphorylation) and toward less efficient anaerobic glycolysis, a phenomenon known as the Warburg effect