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GLP-1 medications work largely by reducing appetite

In some embodiments, the otic pharmaceutical formulation comprises between about 60% to about 70% by weight of the triglycerides

While animal studies show a good safety profile, a theoretical risk involving its pro-angiogenic effects and potential cancer promotion is a point of consideration, though no evidence has supported this risk in practice

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In comparison, patients who used retatrutide (8 mg and 12 mg once weekly) lost 17.5% at 24 weeks and 24.2% of their body weight after 48 weeks in phase 2 clinical trials