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Given the central role of ROS homeostasis in health and disease, targeting ROS and their mediated ROS balancing pathways holds great therapeutic potential [556, 557]

The move, however, was met with strong opposition from compounders, which sued the regulator under the banner of the Outsourcing Facilities Association (OFA) trade group

This protective action likely involves regulating antioxidant gene expression via Nrf2 activation, diminishing excessive ROS accumulation, and reducing oxidative damage markers (e.g., 3-NT and 4-HNE), as evidenced by J Fan et al.s study on STZ-induced diabetic mouse wounds treated with PCs (Fan et al., 2021)

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10.1038/ncb3052 15 ChasseaudL