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Among them, catechin ECG had the most significant effect due to the therapeutic effect of ECG through the BBB, reducing A plaques in the brains of APP/PS1 mice and thus protecting neurons from damage (111)

There are also concerns about its impact on moles and the potential long-term effects on the immune system, which remain largely unknown

Globally, more than 100 million people are affected by DM, which is considered one of the five leading causes of death (Abbas1 et al., 2021