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Emissions outcome measures should include at least: Total Particulate Matter (TPM) yield per puff [Y TPM , (mg/puff)], TPM mass concentration [C TPM , (mg/mL)], and aerosol mass ratio of every constituent listed in the un-puffed E-Liquid [f constituent , (mg constituent/mg TPM)]

In addition, unlike the middle-aged and elderly who are sensitive to nicotine and tar content, the nicotine and tar content tended to be high, unlike the light design, perhaps because it was sought by the younger generation

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Examples include overheating during use, releasing excessive heat, or leaking harmful substances

5% to 20% of the US population gets the flu every year, resulting in 31.4 million outpatient visits annually