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The follow-up pivotal trial (METAOD006 / OPTIONS) enrolled a larger cohort and failed to replicate statistically significant weight loss, which led Metabolic Pharmaceuticals to halt the formal drug development program in 2007

Therefore, parenteral cyanocobalamin should be administered to a pregnant woman if the benefits outweigh the risks (10, 11)

I inject in the bathroom because I can lock the kids out and take my time, if needed

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Choking and blackouts can also be an issue at this level of intoxication