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At week 16, the primary end point of the trial, all patients were crossed over to open-label infliximab therapy through 50 weeks

Similarly, significant correlation was also found between the action of MB and its derivatives on neuroprotection and mitochondria membrane potential (Figure 4E) and between the EC50 of MB and its derivatives on ROS production and mitochondria membrane potential collapse induced by glutamate insult (Figure 4F)

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213 The microbiota predominantly consists of bacteria, with smaller populations of fungi, viruses, archaea, and protozoa

Targeting this vulnerability could be valuable in CRC treatment by exploiting cancer cells sensitivity to oxidative damage