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Collectively, these findings demonstrate that SLE is characterized by mTOR pathway hyperactivation and distinct T cell metabolic reprogramming favoring glycolysis and FAS, which disrupts Th17/Treg balance and drives autoimmunity, positioning metabolic intervention as a viable treatment strategy

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[DOI] [PMC free article] [PubMed] [Google Scholar] 84.Fattorossi A., Biselli R., Casciaro A., Tzantzoglou S., de Simone C

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